Spinal Cord Syndromes

Syndromes, causes and clinical signs Syndrome Causes Clinical Features Complete transection TraumaInfectionTransverse myelitisTumour Complete loss of motor and sensory function below the level of the lesion Hemisection TraumaMSAbscess Ipsilateral loss of motor function and light touch below the lesionContralateral loss of pain/temperature below the lesionipsilateral loss of pain/temperature AT the level of the lesion Central […]

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Blood Gases

I’m going to focus on Arterial blood gases here. Venous gases are close enough in well people, but beware in critical illness there is divergence between arterial and venous samples, particulary in CO2, lactate and pH. Method FiO₂ Calculator 713 x 0.21 = 150 mm Hg Differential Diagnosis HAGMA (CATMUDPILES or LTKR) NAGMA (CAGE, ABCD, […]

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Tracheostomy disasters

Failing to oxygenate/ventilate(any invasive vent, not just traches) DOPES Displacement too deep (unlikely, unless all of: small patient, low puncture site, and adjustable flange trache) too shallow – opening may be against posterior wall in soft tissue – rapidly expanding subcutaneous emphysema completely out Obstruction sputum plug blood/clot plug inner cannula blockage only kinking speaking […]

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TIPSS

Transjugular Intrahepatic PortoSystemic Shunt Flash Cards!   Click here to start flashcard deck[qdeck] [q unit=”Procedures” topic=”TIPSS”] Mechanism of action of TIPSS [a] TIPSS involves accessign the internal jugular vein and IVC to place a stent between hepatic and portal veins using a needle. – High pressure in portal system contributes to major complications of liver […]

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AFLF vs CDLD

Compare and contrast Acute Fulminant Liver Failure (AFLF) and Chronic Decompensated Liver Disease (CDLD) History AFLF CDLD – Acute ingestion (eg paracetamol)– Drug interactions– Viral– Ischaemic– Post-operative– Herbal / alternative Rx eg St John’s Wort – Chronic liver disease– Encephalopathy– Hepatitis (eg chronic Hep C)– GI bleeds Examination AFLF CDLD Jaundice YES YES Coma YES […]

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Dexmedetomidine

Here’s a flash card version of the WTET post on Dexmedetomidine Click here to start flashcard deck[qdeck] [q unit=”Pharmacology” topic=”Dexmedetomidine”] Rationale for Dexmedetomidine [a] Sedation practice varies widely around the world. Propofol and Midazolam are the mainstays of sedation, in addition to an opiate as an antitussive. Traditional first line agents act mainly via GABA. […]

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Furosemide

Alas, no longer Frusemide.   Click here to start flashcard deck[qdeck] [q unit=”Pharmacology” topic=”Frusemide”] Potential indications for the use of Furosemide [a] Cardiovascular indications– Diuresis to decrease fluid balance, thought to be associated with improved mortality– Preload reduction by volume reduction and venodilation– Hyperkalemia and hypercalcemia Toxicological and endocrine indications– Diuresis to force urine output, […]

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Cerebral Herniation Syndromes

There are several cerebral herniation syndromes. Lets drill them     Click here to start flashcard deck[qdeck] [q unit=”Neurology” topic=”Cerebral_Herniation_Syndromes”] Falcine Herniation 1. Structures involved and Radiological features2. Clinical features [a] 1. Displacement of cingulate gyrus under falx cerebri 2. Leg weakness (contralateral)  [q unit=”Neurology” topic=”Cerebral_Herniation_Syndromes”] Midline Shift 1. Structures involved and Radiological features2. Clinical features [a] […]

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Fungi and Antifungal Therapy

Types of Fungi: Yeasts (single celled) Molds (multicellular, hyphated) Dimorphous (can have yeast and mold forms) – very common for human pathogens Fungal components Nucleus (they’re eukaryotes after all, where the DNA lives) Cytosol (with organelles, where the proteins are made) Cell membrane (regulates transmembrane transport) Cell wall (structural integrity to the cell) Examples of […]

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