Reverse Halo Sign

Great little article on a DDx flowchart for the Reverse Halo Sign on CT. Godoy MC, Viswanathan C, Marchiori E, Truong MT, Benveniste MF, Rossi S, Marom EM. The reversed halo sign: update and differential diagnosis. Br J Radiol. 2012 Sep;85(1017):1226-35. doi: 10.1259/bjr/54532316. Epub 2012 May 2. PMID: 22553298; PMCID: PMC3487053.

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Platform Trials

Explain it to me. Also known as Umbrella trials, or Basket trials (but Platform trial sounds cooler), they focus on the disease of interest, and are based on a master protocol which allows for varying groups for analysis against a control group. Technically, they are a type of Adaptive, Multi-arm, Multi-stage trial (but even better) […]

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Management of high ICP: The SIBICC Algorithm

Hawryluk, G.W.J., Aguilera, S., Buki, A. et al. A management algorithm for patients with intracranial pressure monitoring: the Seattle International Severe Traumatic Brain Injury Consensus Conference (SIBICC). Intensive Care Med 45, 1783–1794 (2019). https://doi.org/10.1007/s00134-019-05805-9 Tier ZERO – Basic neuroprotective care, irrespective of ICP Tier ONE ICP-lowering techniques Targets Actions Tier TWO ICP-lowering techniques Targets as above, except: Actions Tier […]

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Intravenous Chalk

It’s a commonly reported chemical reaction that IV calcium given in the same line as IV Bicarbonate causes the formation of Calcium Carbonate (i.e. limestone) in the IV. But does it really? (spoiler alert: YES!) It’s pretty quick too – I made a little video with the help of my friends in the Pathology Lab. […]

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CAR-T Cell Therapy

This is a new type of cancer treatment for certain malignancies where a patient’s blood undergoes apheresis to isolate the T-cells. These undergo gene insertion to express Chimeric Antigen Receptors for the specified target cancer. Cells are propagated in vitro then infused back into the patient where they target and kill the cancer cells. Key […]

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ACDF – Post-operative management

Risk factors for airway-related complications after surgery, specific to this surgery type / population Causes of upper airway obstruction specific to this type of surgery Signs of post-operative airway obstruction post cervical spine surgery Specific airway management strategies after cervical spine surgery (starting PRIOR to extubation)

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