Good Guidance

Locations of major topic guidelines, in alphabetical order by subject Death & Organ Donation: ANZICS Statement DKA (adult): JBDSIC (3ed) 2022 ECMO Guidance: ELSO Guidelines Extracorporeal treatments in toxicology: EXTRIP Recommendations Resuscitation: ARC Guidelines TBI: BTF Guidelines (4ed) 2016 Patient Transport: ACEM/ANZCA/CICM Guidance British Thoracic Society: BTS Guidelines

C-spine imaging

There are really 3 types of thing to image when we are talking about C-spine injury The modality of choice depends on the structure of interest: Various features favour one over the other: Feature CT MRI Availability Widely available Limited availability Gold standard for: Bony injury Soft tissue & neural injury Radiation Some (potentially vulnerable … Read more

Reverse Halo Sign

Great little article on a DDx flowchart for the Reverse Halo Sign on CT. Godoy MC, Viswanathan C, Marchiori E, Truong MT, Benveniste MF, Rossi S, Marom EM. The reversed halo sign: update and differential diagnosis. Br J Radiol. 2012 Sep;85(1017):1226-35. doi: 10.1259/bjr/54532316. Epub 2012 May 2. PMID: 22553298; PMCID: PMC3487053.

Platform Trials

Explain it to me. Also known as Umbrella trials, or Basket trials (but Platform trial sounds cooler), they focus on the disease of interest, and are based on a master protocol which allows for varying groups for analysis against a control group. Technically, they are a type of Adaptive, Multi-arm, Multi-stage trial (but even better) … Read more

Management of high ICP: The SIBICC Algorithm

Hawryluk, G.W.J., Aguilera, S., Buki, A. et al. A management algorithm for patients with intracranial pressure monitoring: the Seattle International Severe Traumatic Brain Injury Consensus Conference (SIBICC). Intensive Care Med 45, 1783–1794 (2019). https://doi.org/10.1007/s00134-019-05805-9 Tier ZERO – Basic neuroprotective care, irrespective of ICP Tier ONE ICP-lowering techniques Targets Actions Tier TWO ICP-lowering techniques Targets as above, except: Actions Tier … Read more