This calculator uses common variables to give estimates of mortality and need for intervention based on the Glasgow-Blatchford Score, the AIMS65 score and the MELD 3.0 score.
Combined AIMS65, Glasgow Blatchford, and MELD 3.0
One row per input • Live updating • CC-OrangeCard
Demographic
Age: 40 years
History
Examination
Systolic blood pressure: 120 mm Hg
Laboratory
Hemoglobin: 120 g/L
INR: 1.0
Sodium: 137 mmol/L
Urea (BUN): 5.0 mmol/L
Creatinine: 88 μmol/L
Bilirubin: 17 μmol/L
Albumin: 35 g/L
AIMS65
0
In-hospital mortality ≈ 0.3%
Glasgow Blatchford Score (GBS)
0
Low risk (0–1): suitable for outpatient management
MELD 3.0 (use natural log and bounds):
Convert: bilirubin (μmol/L → mg/dL) = bili/17.1; creatinine (μmol/L → mg/dL) = cr/88.4; albumin (g/L → g/dL) = alb/10. Clamp: bili ≥1, inr ≥1, creatinine ≥1 with upper cap 3.0 mg/dL (or set to 3.0 if dialysis), sodium 125–137 mEq/L, albumin 1.5–3.5 g/dL. For ages 12–17, add the 1.33 “female” points regardless of sex.
Formula (rounded to nearest integer):
MELD3.0 = round( 1.33×Female + 4.56×ln(bili) + 0.82×(137−Na) − 0.24×(137−Na)×ln(bili) + 9.09×ln(INR) + 11.14×ln(Cr) + 1.85×(3.5−Alb) − 1.83×(3.5−Alb)×ln(Cr) + 6 )
Survival at time t days: S(t) = 100 × [S₀(t)]^(0.17698 × (MELD − 3.56))
with S₀(t): {15:0.991, 30:0.981, 45:0.971, 60:0.963, 75:0.955, 90:0.946}.
References
Kim WR, Mannalithara A, Heimbach JK, et al. MELD 3.0: The Model for End-Stage Liver Disease Updated for the Modern Era. Gastroenterology. 2021;161(6):1887-1895.e4. PMID: 34481845. doi: 10.1053/j.gastro.2021.08.050.
OPTN/UNOS. MELD–PELD Calculator User Guide. (MELD 3.0 bounds and rules). Available online. (See albumin, sodium, creatinine caps and dialysis rule).
Kwong AJ, Kim WR, et al. MELD 3.0 for adolescent liver transplant candidates. Hepatology. 2023. PMID: 36943091. (Adolescents aged 12–17 receive the 1.33 points regardless of sex.)
Blatchford O, Murray WR, Blatchford M. A risk score to predict need for treatment for upper-GI haemorrhage. Lancet. 2000;356(9238):1318-21. PMID: 11073021. doi: 10.1016/S0140-6736(00)02816-6.
Saltzman JR, Tabak YP, Hyett BH, et al. A simple risk score (AIMS65) for in-hospital mortality in upper GI bleeding. Gastrointest Endosc. 2011;74(6):1215-1224. PMID: 22136799. doi: 10.1016/j.gie.2011.07.055.