ECMO Sweep Gas Oxygen Fraction with In-line Nitric Oxide v1.1
Calculates the oxygen fraction and gas flow reaching an ECMO oxygenator after in-line nitric oxide addition.
Nitric oxide carrier flow
0.128 L/min
Added nitric oxide / nitrogen stream
Total mixed flow before sampling
5.128 L/min
Base flow plus nitric oxide stream
Final flow to oxygenator
4.898 L/min
After optional sample loss
Final oxygen fraction
97.5%
Gas entering oxygenator
1. Mixer oxygen fraction = mixer oxygen setting / 100
2. Nitric oxide carrier flow = (nitric oxide ppm × base flow) / (800 − nitric oxide ppm)
3. Mixed flow before sampling = base flow + nitric oxide carrier flow
4. Final oxygen fraction = (mixer oxygen fraction × base flow) / mixed flow before sampling
5. Final oxygenator flow = mixed flow before sampling − 0.23 L/min, if sample loss is subtracted
Assumes an 800 ppm nitric oxide in nitrogen source, with the added carrier stream containing no oxygen.
- Mallinckrodt Pharmaceuticals. INOmax DSIR Pocket Guide, Series 3 software. 2014.
- United States Food and Drug Administration. INOmax (nitric oxide) gas prescribing information. 2023.
- Mallinckrodt Pharmaceuticals. INOmax DSIR Plus Operation Manual. Series 3 software.