Vancomycin Level Estimation Calculator

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This is likely to be disastrously wrong, I’m just tinkering here with the code to see how a calculation package might look. Please, do not use any of this information.

Vancomycin Level Estimation Calculator

Exploratory one-compartment estimate from intermittent doses and measured levels
Version 1.0.0
Exploratory estimate — not a dosing recommendation.

This preserves the legacy one-compartment structure with a safety correction that prevents elimination fitting across an intervening dose. It assumes a fixed 1000 mg/h infusion rate and first-order elimination. It does not use renal function, Bayesian population pharmacokinetics or estimate area under the concentration–time curve (AUC). Confirm dosing decisions using an approved local therapeutic drug monitoring method.

Patient and model

kg
L/kg
h

The default half-life is used unless at least two eligible declining levels permit log-linear estimation. Eligible levels are outside every infusion and its 2-hour post-infusion exclusion window. Levels used together to estimate elimination must follow the same most recent dose, with no intervening dose.

Add dose

mg
local time
Infusion rate1000mg/h
Calculated duration1.00h

Add measured level

mg/L
local time
No clinical values are intentionally saved by this control.